Abstract The Platelet Derived Growth Factor (PDGF) family of ligands have well established functions in the induction of cell proliferation and migration during development, tissue homeostasis and interactions between tumours and stroma.However, the mechanisms by which leather-strapon these actions are executed are incompletely understood.Here we r
Population-based cancer screening through community participation: Outcome of a district wide oral cancer screening program from rural Kannur, Kerala, India
Background: Oral cancer is a major public health challenge, and about one-fifth of all oral cancer cases reported globally are from India.In spite of the potential for early detection by simple visual examination, the majority of patients report in later stages of the disease, especially in Drain Outlet Hose Extension low and middle-income countrie
Electrical stimulation of chicken embryo development supports the Inside story scenario of human development and evolution
Abstract Animal evolution is driven by random mutations at the genome level.However, it has long been suggested that there exist physical constraints which limit the set of possible outcomes.In craniate evolution, it has been observed that head features, notably in the genus homo, can be ordered in a morphological diagram such that, as the brain ex
An Endosomal NAADP-Sensitive Two-Pore Ca2+ Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling
Membrane contact sites are regions of close apposition between organelles that facilitate information transfer.Here, we Chase Rack reveal an essential role for Ca2+ derived from the endo-lysosomal system in maintaining contact between endosomes and the endoplasmic reticulum (ER).Antagonizing action of the Ca2+-mobilizing messenger NAADP, inhibiting
THE CROCHETING OF THE IMPLEMENTATION OF PANCASILA VALUES ON THE REGIONAL GOVERNMENT BUDGET
This study examines how to crochet the implementation of Pancasila values on the regional government budget through a case study in Bantul Regency.The study focused on the implications of implementing Pancasila values which have been carried out at the Regional Government of Bantul as an effort to apply Pancasila in the government.Through the imple